Proteome database of cultured human cells

Primary cultures of human-derived cell strains and permanent cell lines are valuable research resources with which various investigations into cell functions and pathological deviations are able to be performed avoiding human ethical problems. The characterization and profiling of the behavior of cells in different culture conditions by using the methods of proteomics might offer useful information in the biomedical researches of human cell physiology and pathology. The TMIG-2DPAGE Proteome Database is being developed for the proteomic analysis of molecular mechanisms of aging and age-dependent cell dysfunction.

[Cellular Aging]

TIG-3, human diploid fibroblast cell strain
(HTML format)

SH-SY5Y, human neuroblastoma cell line
(XML format without RDB)
[95%-Oxygen stress]

HUVEC, human umbilical vein endothelial cells
(XML format without RDB)
[Premature aging]

Werner's Syndrome-related Proteome of Human Skin Fibroblasts
(under construction)

Human CSF Proteome, 2D-DIGE analysis
(Under construction for collaborative research)

Methods in Proteomics Performed in TMIG Proteomics Collaboration Center.

Web Sites for Proteomics:

WORLD-2DPAGE Index to federated 2-D PAGE database


ExPASy Proteomics tools

Mascot Search



Elemental Properties of LBNL Isotopes Project

Related Web Sites

SARS coronavirus protein sequences are available on Wsiss-Prot Database

FindMod tool: a tool that is served on ExPASy server for predicting potential protein post-translational modifications and finding potential single amino acid substitutions by pepide mass mapping

Presented by Tosifusa Toda, Megumi Nakamura, Hiraku Morisawa and Mikako Hirota
TMIG Proteomics Collaboration Center
Tokyo Metropolitan Institute of Gerontology
Date of the last modification : Oct. 6, 2006